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Continue to ChatBron: 24-02-2020: https://www.thelancet.com/action/showPdf?pii=S1473-3099%2820%2930086-4 Aim To describe the CT findings across different time points throughout the disease course Key finding COVID-19 pneumonia manifests with chest CT-scan abnormalities, even in asymptomatic patients Rapid evolution from focal unilateral to diffuse bilateral ground-glass opacities that progressed to or co-existed with consolidations within 1-3 weeks Combining imaging features with clinical and laboratory findings could facilitate early diagnosis of COVID-19 pneumonia Summary Retrospective study performed at two centres in Wuhan 81 patients admitted to one of the hospitals between Dec 20, 2019 and Jan 23, 2020, with confirmed COVID-19 pneumonia, were retrospectively included in this study Patients were grouped according to interval between symptoms onset and first CT scan: group 1 → scan performed before symptoms group 2 → scan performed ≤ 1 week after symptoms onset group 3 → scan performed > 1 to 2 weeks after symptoms onset group 4 → scan performed > 2 to 3 weeks after symptoms onset Characteristics full cohort: mean age: 49.5 (25-81) 52% male, 48% female most common clinical symptoms: fever 73% dry cough 59% headache 6% generalised weakness 9% mean number of involved lung segments: 10.5, with right lower lobes most commonly affected Typical pattern of CT imaging features per group (figure): group 1: unilateral and multifocal ground-glass opacities group 2: lesions quickly evolved to bilateral and diffuse ground-glass opacities, with a relative decrease in the frequency of ground-glass and transition to consolidation and mixed-pattern group 3-4: ground-glass opacities continued to decrease, while consolidation became the second most common pattern The imaging characteristics are non-specific and bear some resemblance https://heelkunde.nl/nieuws/nieuwsbericht?newsitemid=31948843